Preferred Label : Gallium Ga 68 Boclatixafortide;
NCIt synonyms : [68Ga] Pentixafor; Ga68 Pentixafor; 68Ga Pentixafor; Ga-68 Pentixafor; Pentixafor Gallium GA-68; Gallium Ga 68 Pentixafor; CPCR4-2 GA-68; 68GA-CPCR4-2;
NCIt related terms : GALLIUM (68GA) BOCLATIXAFORTIDE;
NCIt definition : A radioconjugate composed of a synthetic, cyclic pentapeptide analog of stromal-cell
derived factor-1 (SDF-1 or CXCL12), which is a ligand for chemokine receptor C-X-C
chemokine receptor type 4 (CXCR4), that is radiolabeled, via the macrocyclic chelating
agent dodecanetetraacetic acid (DOTA), with the radioisotope gallium Ga 68 (Ga68;
68Ga), with potential use for imaging CXCR4-expressing cells upon positron emission
tomography (PET)/computed tomography (CT). Upon administration of 68Ga pentixafor,
the pentixafor moiety targets and binds to CXCR4-expressing cancer cells. Upon PET/CT,
CXCR4-expressing cancer cells can be visualized and the expression status of the receptor
can be assessed. CXCR4, a marker of poorly differentiated cells, is overexpressed
on various cancer cells, and plays a key role in tumor growth, progression, invasiveness
and metastasis.;
UNII : Y92N1ZLI87;
CAS number : 1345698-96-5; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 1345698-96-5
alt lien vers site G-SRS target _blank img src /img/logos/logo_g-srs.png alt Logo
G-SRS /a ;
Origin ID : C141632;
UMLS CUI : C4042170;
Currated CISMeF NLP mapping
- Semantic type(s)
- UMLS correspondences (same concept)
- concept_is_in_subset
- has_target
