NCIt definition : Stage IVA1 includes: T1-4, N0-2, M0, B2. T1: Limited patches, papules, and/or plaques
covering less than 10% of the skin surface. T2: Patches, papules, or plaques covering
10% or more of the skin surface. T3: One or more tumors (equal or greater than 1 cm
in diameter). T4: Confluence of erythema covering 80% or more of body surface area.
N0: No clinically abnormal peripheral lymph nodes; biopsy not required. N1: Clinically
abnormal peripheral lymph nodes; histopathology Dutch grade 1 or National Cancer Institute
(NCI) LN0-2. N2: Clinically abnormal peripheral lymph nodes; histopathology Dutch
grade 2 or NCI LN3. M0: No visceral organ involvement. B2: High blood tumor burden:
1,000 per microliter or more Sezary cells with positive clone. (AJCC 8th ed.);