Poseltinib - CISMeF

Preferred Label : Poseltinib;

NCIt synonyms : 2-Propenamide, N-(3-((2-((4-(4-methyl-1-piperazinyl)phenyl)amino)furo(3,2-d)pyrimidin-4-yl)oxy)phenyl)-;

NCIt definition : An inhibitor of Bruton's tyrosine kinase (BTK) with potential anti-inflammatory activity. Upon administration, poseltinib inhibits the activity of BTK and prevents the activation of the B-cell antigen receptor (BCR) signaling pathway. This prevents the activation of BTK-mediated inflammatory pathways.;

UNII : D01E4B1U35;

InChIKey : LZMJNVRJMFMYQS-UHFFFAOYSA-N;

CAS number : 1353552-97-2;

Molecule name : LY3337641; HM71224;

NCI Metathesaurus CUI : CL539405;

Details

Origin ID

C141273;

UMLS CUI

C4683676;

Currated CISMeF NLP mapping
- poseltinib [MeSH concept]
- poseltinib [MeSH Supplementary Concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- poseltinib [MeSH Supplementary Concept]
concept_is_in_subset
- CTRP Agent Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
has_target
- Tyrosine-Protein Kinase BTK [NCIt concept]

Keyword's position in hierarchy(ies) :

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