NCIt definition : A semisynthetic analog of Bleomycin, a mixture of several basic glycopeptide antineoplastic
antibiotics isolated from Streptomyces verticillus. Peplomycin forms complexes with
iron that reduce molecular oxygen to superoxide and hydroxyl radicals that cause single-
and double-stranded breaks in DNA. This agent appears to show greater antitumor activity
than bleomycin; its use is limited due to pulmonary toxicity. (NCI04);
UNII : 56H9L80NIZ;
InChIKey : QIMGFXOHTOXMQP-GFAGFCTOSA-N;
CAS number : 68247-85-8; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 68247-85-8
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