CIC/DUX4 Fusion Protein

Preferred Label : CIC/DUX4 Fusion Protein;

NCIt synonyms : Protein Capicua Homolog/Double Homeobox 4 Fusion Protein; CIC-DUX4 Fusion Protein; Protein Capicua Homolog::Double Homeobox 4 Fusion Protein; CIC::DUX4 Fusion Protein;

NCIt definition : A fusion protein encoded by the CIC/DUX4 fusion gene. This protein is comprised of the majority of the protein capicua homolog, including the DNA-binding high-mobility group (HMG)-box and 15 of 16 putative MAPK phosphorylation sites, fused to the C-terminus of double homeobox protein 4, which results in the loss of both of its DNA-binding homeodomains.;

NCI Metathesaurus CUI : CL537826;

Details

Origin ID

C139676;

UMLS CUI

C4682438;

Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- CIC/DUX4 Fusion Gene [NCIt concept]
- Fusion Gene [NCIt concept]
related_to_genetic_biomarker
- CIC Gene [NCIt concept]
- DUX4 Gene [NCIt concept]

Keyword's position in hierarchy(ies) :

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