Icotinib - CISMeF

Preferred Label : Icotinib;

NCIt synonyms : (1,4,7,10)Tetraoxacyclododecino(2,3-g)quinazolin-4-amine, N-(3-ethynylphenyl)-7,8,10,11,13,14-hexahydro-;

NCIt definition : An orally available quinazoline-based inhibitor of epidermal growth factor receptor (EGFR), with potential antineoplastic activity. Icotinib selectively inhibits the wild-type and several mutated forms of EGFR tyrosine kinase. This may lead to an inhibition of EGFR-mediated signal transduction and may inhibit cancer cell proliferation. EGFR, a receptor tyrosine kinase, has been upregulated in a variety of cancer cell types.;

UNII : 9G6U5L461Q;

InChIKey : QQLKULDARVNMAL-UHFFFAOYSA-N;

CAS number : 610798-31-7;

Molecule name : BPI-2009;

NCI Metathesaurus CUI : CL433010;

Codes from synonyms : 264;

Details

Origin ID

C138996;

UMLS CUI

C2604307;

Automatic exact mappings (from CISMeF team)
- Icotinib [ICD-11 Extension code]
- icotinib [ATC Code]
Currated CISMeF NLP mapping
- icotinib [MeSH Supplementary Concept]
- icotinib [MeSH concept]
Semantic type(s)
- Immunologic Factor [UMLS semantic type]
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- icotinib [MeSH Supplementary Concept]
- icotinib [MeSH concept]
- icotinib [ATC Code]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- HemOnc Agent Terminology [NCIt concept]
has_salt_form
- Icotinib Hydrochloride [NCIt concept]
is_free_acid_or_base_form_of
- Icotinib Hydrochloride [NCIt concept]

Keyword's position in hierarchy(ies) :

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