High Grade B-Cell Lymphoma with MYC and BCL2 and/or BCL6 Rearrangements

Preferred Label : High Grade B-Cell Lymphoma with MYC and BCL2 and/or BCL6 Rearrangements;

NCIt synonyms : HGBL with MYC and BCL2 and/or BCL6 Rearrangements; High-Grade B-Cell Lymphoma with MYC and BCL2 and/or BCL6 Rearrangements;

NCIt definition : High-grade B-cell lymphoma characterized by the abnormal rearrangement of MYC gene, BCL2 gene, and/or BCL6 gene. Patients with this type of lymphoma usually respond poorly to standard treatments and have a poor prognosis.;

Neoplastic status : Malignant;

NCI Metathesaurus CUI : CL519964;

Détails

Origin ID

C138195;

UMLS CUI

C4524190;

Automatic exact mappings (from CISMeF team)
- High grade B-cell lymphoma with MYC and BCL2 and/or BCL6 rearrangements [ICD-11 Extension code]
- High grade B-cell lymphoma with MYC and BCL2 and/or BCL6 rearrangements (morphologic abnormality) [SNOMED CT concept]
- High grade B-cell lymphoma with MYC and/ or BCL2 and/or BCL6 rearrangement [ORDO Disease]
- high-grade B-cell lymphoma double-hit/triple-hit [DO Concept]
Disease excludes abnormal cell
- Lymphocyte Predominant Cell [NCIt concept]
- Neoplastic T-Lymphocyte and Neoplastic Natural Killer Cell [NCIt concept]
- Reed-Sternberg Cell [NCIt concept]
Disease excludes normal cell origin
- EBV-Transformed Mature B-Lymphocyte [NCIt concept]
- Myeloid Cell [NCIt concept]
- Plasma Cell [NCIt concept]
- Precursor B-Lymphoblast [NCIt concept]
Disease may have findings
- Aggressive Clinical Course [NCIt concept]
Has associated anatomic sites
- Hematopoietic and Lymphatic System [NCIt concept]
Has cytogenetic abnormalities
- MYC Gene Rearrangement [NCIt concept]
Semantic type(s)
- Neoplastic Process [UMLS semantic type]
UMLS correspondences (same concept)
- High grade B-cell lymphoma with MYC and BCL2 and/or BCL6 rearrangements (disorder) [SNOMED CT concept]
- High grade B-cell lymphoma with MYC and BCL2 and/or BCL6 rearrangements (morphologic abnormality) [SNOMED CT concept]
- High-grade B-cell lymphoma, with MYC and BCL2 and/or BCL6 rearrangements [MedDRA LLT]
concept_is_in_subset
- CTRP Disease Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
disease_excludes_finding
- Benign Cellular Infiltrate [NCIt concept]
disease_has_abnormal_cell
- Abnormal Lymphocyte [NCIt concept]
- Malignant Cell [NCIt concept]
- Neoplastic B-Lymphocyte [NCIt concept]
- Neoplastic Cell [NCIt concept]
- Neoplastic Hematopoietic and Lymphoid Cell [NCIt concept]
- Neoplastic Large B-Lymphocyte [NCIt concept]
- Neoplastic Lymphocyte [NCIt concept]
disease_has_finding
- Diffuse Pattern [NCIt concept]
- Malignant Cellular Infiltrate [NCIt concept]
disease_has_grade
- High Grade [NCIt concept]
disease_has_molecular_abnormality
- Clonal Immunoglobulin Gene Rearrangement [NCIt concept]
- Clonal Immunoglobulin Kappa Light Chain Gene Rearrangement [NCIt concept]
disease_has_normal_cell_origin
- B-Lymphocyte [NCIt concept]
- Hematopoietic and Lymphoid Cell [NCIt concept]
- Lymphocyte [NCIt concept]
- Mature B-Lymphocyte [NCIt concept]
disease_has_normal_tissue_origin
- Hematopoietic and Lymphoid Tissue [NCIt concept]
- Lymphoid Tissue [NCIt concept]
disease_has_primary_anatomic_site
- Hematopoietic and Lymphatic System [NCIt concept]
- Lymphatic System [NCIt concept]
disease_mapped_to_gene
- MYC Gene [NCIt concept]
disease_may_have_molecular_abnormality
- Clonal Immunoglobulin Heavy Chain Gene Rearrangement [NCIt concept]
- Clonal Immunoglobulin Lambda Light Chain Gene Rearrangement [NCIt concept]
pathogenesis_of_disease_involves_gene
- MYC Gene [NCIt concept]
- MYC wt Allele [NCIt concept]

Position du mot-clé dans l'(les) arborescence(s) :

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