Preferred Label : Thymosin Beta-4, Y-Chromosomal;
NCIt synonyms : TMSB4Y; Thymosin Beta-4, Y Isoform;
NCIt definition : Thymosin beta-4, Y-chromosomal (44 aa, 5 kDa) is encoded by the human TMSB4Y gene.
This protein is involved in the inhibition of actin polymerization.;
NCIt note : Since amino acids 2-5 of thymosin beta-4, Y-chromosomal is identical to that of thymosin
beta-4., thymosin beta-4, Y-chromosomal may be cleaved to release a biologically active
tetrapeptides called hematopoietic system regulatory peptide, for which the synthetic
acetylated peptide is called seraspenide. Seraspenide causes G1 phase arrest for hematopoietic
stem cells.; Thymosin beta-4 and thymosin beta-4, Y-chromosomal are identical except for amino
acid positions 6, 30 and 39.;
NCI Metathesaurus CUI : CL524962;
Origin ID : C137964;
UMLS CUI : C4521291;
Automatic exact mappings (from CISMeF team)
OMIM relation
Semantic type(s)
gene_encodes_gene_product
gene_product_has_associated_anatomy
gene_product_has_biochemical_function
gene_product_is_element_in_pathway
gene_product_plays_role_in_biological_process