NCIt definition : An orally bioavailable, non-steroidal selective androgen receptor modulator (SARM),
with potential tissue-selective androgenic/anti-androgenic activities. Upon oral administration,
vosilasarm acts as an agonist in select tissues, such as skeletal muscle and bone,
where it binds to and activates androgen receptors (ARs). In the prostate and breasts,
vosilasarm acts as an antagonist and blocks AR activation and AR-mediated cellular
proliferation. Therefore, this agent may improve bone formation and muscle mass and
strength, and may inhibit both the growth of the prostate in males and AR-dependent
breast cancer cell proliferation. Compared to anabolic agents, SARMs have reduced
androgenic properties.;
UNII : 4O87Q44KNC;
InChIKey : XMBUPPIEVAFYHO-KPZWWZAWSA-N;
CAS number : 1182367-47-0;
Drug name : Testolone;
Molecule name : RAD 140; RAD-140; EP 0062; EP-0062;
See also inter- (CISMeF)