Elliptinium Acetate

Preferred Label : Elliptinium Acetate;

NCIt synonyms : 9-Hydroxy-2,5,11-trimethyl-6H-pyrido[4,3-b]carbazolium Acetate (Salt); 9-Hydroxy-2-methylellipticinium Acetate; N-2-Methyl-9-hydroxyellipticinium Acetate; Elliptinium;

NCIt related terms : 6H-Pyrido[4, 3-b]carbazolium, 9-hydroxy-2,5,11-trimethyl-acetate (salt); Celiptium;

NCIt definition : Acetate salt of elliptinium, a derivative of the alkaloid ellipticine isolated from species of the plant family Apocynaceae, including Bleekeria vitensis, a plant with anti-cancer properties. As a topoisomerase II inhibitor and intercalating agent, elliptinium stabilizes the cleavable complex of topoisomerase II and induces DNA breakages, thereby inhibiting DNA replication and RNA and protein synthesis.;

UNII : H9B41234P4;

InChIKey : BOMZMNZEXMAQQW-UHFFFAOYSA-N;

CAS number : 58337-35-2;

Drug name : Celiptium;

Chemical formula : C18H17N2O.C2H3O2;

NSC code : 264137;

Codes from synonyms : NSC0264137;

Details

Origin ID

C1367;

UMLS CUI

C0100593;

Currated CISMeF NLP mapping
- Elliptinium acetate [ICD-11 Extension code]
- elliptinium acetate [Substance BNPC]
- elliptinium acetate [MeSH concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Elliptinium acetate [ICD-11 Extension code]
- elliptinium acetate [Substance BNPC]
- elliptinium acetate [MeSH concept]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- GDC Terminology [NCIt concept]
- GDC Therapeutic Agent Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
- NCIt Antineoplastic Agent Terminology [NCIt concept]
has_free_acid_or_base_form
- Elliptinium [NCIt concept]
is_salt_form_of
- Elliptinium [NCIt concept]

Keyword's position in hierarchy(ies) :

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