Mivobulin Isethionate

Preferred Label : Mivobulin Isethionate;

NCIt related terms : CI-980;

NCIt definition : The isethionate salt of mivobulin, a synthetic colchicine analogue with potential antineoplastic activity. Mivobulin isethionate binds to tubulin, thereby inhibiting microtubule polymerization and mitosis.;

Alternative definition : NCI-GLOSS: An anticancer drug that belongs to the family of drugs called mitotic inhibitors.;

UNII : 8J08028R66;

InChIKey : JEFPWOBULVSOTM-PPHPATTJSA-N;

CAS number : 126268-81-3;

Molecule name : CI-980; CI 980;

Chemical formula : C17H19N5O2.C2H6O4S;

NSC code : 635370;

Codes from synonyms : CDR0000046065; CDR0000044438;

Details

Origin ID

C1357;

UMLS CUI

C0796310;

Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
chemical_or_drug_affects_gene_product
- Tubulin [NCIt concept]
chemical_or_drug_has_mechanism_of_action
- Microtubule Process [NCIt concept]
chemical_or_drug_has_physiologic_effect
- Negative Regulation of Microtubule Polymerization [NCIt concept]
- Negative Regulation of Mitosis [NCIt concept]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- GDC Terminology [NCIt concept]
- GDC Therapeutic Agent Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
- NCIt Antineoplastic Agent Terminology [NCIt concept]
is_component_of_chemotherapy_regimen
- CI-980/Filgrastim [NCIt concept]

Keyword's position in hierarchy(ies) :

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