" /> Beta-Thioguanine Deoxyriboside - CISMeF





Preferred Label : Beta-Thioguanine Deoxyriboside;

NCIt synonyms : 2'-desoxy-6-thioguanosine; 1,9-dihydro-6H-purine-6-thione, 2-amino-9-(2-deoxy-beta-D-erythro-pentofuranosyl); beta-2'-deoxy-6-thioguanosine; BTG; Beta Thioguanine Deoxyriboside; 9H-purine-6-thiol, 2-amino-9-(2-deoxy-beta-D-erythro-pentofuranosyl) monohydrate; beta-2'-deoxythiol guanosine; beta-2'-deoxythioguanosine; B-TGDR; thioguanine 9-beta-D-2'-deoxyriboside;

NCIt related terms : 6H-Purine-6-thione, 2-amino-9-(2-deoxy-.beta.-D-erythro-pentofuranosyl)-1,9-dihydro-; .beta.-Thioguanine deoxyriboside; 9H-Purine-6-thiol, 2-amino-9-(2-deoxy-.beta.-D-erythro-pentofuranosyl)-, monohydrate; Thioguanine 9.beta.D-2'-deoxyriboside; .beta.-2'-Deoxythioguanosine; 6-Mercaptoguaninedeoxyriboside; 2'-Deoxythioguanosine; .beta.-2'-Deoxythiol guanosine; .beta.-2'-Deoxy-6-thioguanosine; ATEGANOSINE;

NCIt definition : A thiopurine nucleoside derivative with antineoplastic activity. After conversion to the triphosphate, beta-thioguanine deoxyriboside is incorporated into DNA, resulting in inhibition of DNA replication. This agent is cytotoxic against leukemia cell lines and has demonstrated some activity against leukemia cells in vivo. Beta-thioguanine deoxyriboside demonstrates antineoplastic activity against 6-thioguanine-resistant tumor cells. (NCI04);

UNII : KR0RFB46DF;

CAS number : 64039-27-6; 789-61-7;

NSC code : 71261;

Codes from synonyms : NSC0071261;

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25/05/2025


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