AKR1B1 wt Allele

Preferred Label : AKR1B1 wt Allele;

NCIt synonyms : ADR; Aldo-Keto Reductase Family 1, Member B1 (Aldose Reductase) Gene; AR; Aldo-Keto Reductase Family 1 Member B wt Allele; ALDR1; Aldo-Keto Reductase Family 1, Member B1 Gene; ALR2;

NCIt definition : Human AKR1B1 wild-type allele is located in the vicinity of 7q33 and is approximately 17 kb in length. This allele, which encodes aldose reductase protein, is involved in the metabolism of glucose, toxic aldehydes and steroids. This gene is associated with the development of diabetic complications.;

NCI Metathesaurus CUI : CL521733;

GenBank Accession Number : J04795;

Details

Origin ID

C133810;

UMLS CUI

C4521369;

Automatic exact mappings (from CISMeF team)
- ADR (body structure) [SNOMED CT concept]
- Aldehyde reductase (substance) [SNOMED CT concept]
- Aldo-keto reductase family 1, member b1 [OMIM gene]
- Androgen receptor [OMIM gene]
- Aortic valve insufficiency [ICD-11 Category]
- Arising in (attribute) [SNOMED CT concept]
- aldehyde reductase [MeSH Descriptor]
- androgen receptor [ORDO Gene]
- drug evaluation [MeSH Descriptor]
- ferredoxin reductase [ORDO Gene]
OMIM relation
- Aldo-keto reductase family 1, member b1 [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
gene_found_in_organism
- Human [NCIt concept]
gene_is_element_in_pathway
- Fructose and Mannose Metabolism Pathway [NCIt concept]
- Galactose Metabolism Pathway [NCIt concept]
- Glycerolipid Metabolism Pathway [NCIt concept]
- Pentose and Glucuronate Interconversions Pathway [NCIt concept]
gene_plays_role_in_process
- Carbohydrate Metabolic Process [NCIt concept]
- Oxidation [NCIt concept]
- Oxidation/Reduction [NCIt concept]
- Steroid Metabolic Process [NCIt concept]

Keyword's position in hierarchy(ies) :

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