aldehyde reductase

Preferred Label : aldehyde reductase;

MeSH definition : An enzyme that catalyzes reversibly the oxidation of an aldose to an alditol. It possesses broad specificity for many aldoses. EC 1.1.1.21.;

MeSH synonym : Aldose Reductase; reductase, aldose; reductase, aldehyde;

MeSH hyponym : aldose reductase ia; xylose reductase; aldose reductase ib; erythrose reductase; Reductase Ib, Aldose; Reductase, Xylose; Reductase Ia, Aldose; Reductase, Erythrose;

MeSH CAS label : Alditol:NAD(P) 1-oxidoreductase;

Registry Number MeSH : EC 1.1.1.21;

Wikipedia link : https://en.wikipedia.org/wiki/Aldehyde reductase;

Is substance : O;

UNII : EC 1.1.1.21;

Details

Origin ID

D000449;

UMLS CUI

C0002003;

ATC code(s)
- aldose reductase inhibitors [ATC Code]
Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Indexing information
- (1-(3,5-difluoro-4-hydroxyphenyl)-1H-pyrrol-3-yl)phenylmethanone [MeSH Supplementary Concept]
- (10-benzyl-(1,2,4)triazino(4,3-a)benzimidazol-3,4(10H)-dion-2-yl)acetic acid [MeSH Supplementary Concept]
- (2,4-bis(4-methoxybenzoyl)pyrrol-1-yl)acetic acid [MeSH Supplementary Concept]
- (2,6-dimethylphenylsulfonyl)nitromethane [MeSH Supplementary Concept]
- (2-(2,4,5-trifluorobenzyl)-7-chloro-3,4-dihydro-2H-1,2,4-benzothiadiazine 1,1-dioxide-4-yl)acetic acid [MeSH Supplementary Concept]
- (2-(2,4,5-trifluorobenzyl)-7-fluoro-3,4-dihydro-2H-1,2,4-benzothiadiazine 1,1-dioxide-4-yl)acetic acid [MeSH Supplementary Concept]
- (2-(4-bromo-2-fluorobenzyl)-7-chloro-3,4-dihydro-2H-1,2,4-benzothiadiazine 1,1-dioxide-4-yl)acetic acid [MeSH Supplementary Concept]
- (2-benzyl-2,3,4,5-tetrahydro-1H-pyrido(4,3-b)indole-8-yl)-acetic acid [MeSH Supplementary Concept]
- (3-benzoylpyrrol-1-yl)acetic acid [MeSH Supplementary Concept]
- (5-(3-thienyl)tetrazol-1-yl)acetic acid [MeSH Supplementary Concept]
- (6-methyl-3-(4,5,7-trifluorobenzothiazol-2-ylmethyl)pyrrolo(2,3-b)pyridin-1-yl)acetic acid [MeSH Supplementary Concept]
- (Z)2-(5-(4-methoxybenzylidene)-2,4-dioxothiazolidin-3-yl)acetic acid [MeSH Supplementary Concept]
- 1-((4-bromophenyl)sulfonyl)hydantoin [MeSH Supplementary Concept]
- 1H,7H-5a,6,8,9-tetrahydro-1-oxopyrano(4,3-b)(1)benzopyran-3-acetic acid [MeSH Supplementary Concept]
- 2,2',4,4'-tetrahydroxybenzophenone [MeSH Supplementary Concept]
- 2-(3,4,5-trimethoxybenzoyl)-4,4-diethyl-3,5-isoxazolidinedione [MeSH Supplementary Concept]
- 2-(3,4-dihydroxyphenyl)-6-hydroxypyrido(1,2-a)pyrimidin-4-one [MeSH Supplementary Concept]
- 2-(3-(4-methoxyphenyl)-1,2,4-oxadiazol-5-yl)acetic acid [MeSH Supplementary Concept]
- 2-methyl-1-oxo-1H-phenalene-3-acetic acid [MeSH Supplementary Concept]
- 3'-O-((6-(2-nitro-4-azidophenylamino)hexyl)carbamoyl)quercitrin [MeSH Supplementary Concept]
- 3,4-di-O-caffeoylquinic acid [MeSH Supplementary Concept]
- 3,4-dihydro-4-oxo-5,6-cyclohexano-3-((5-(trifluoromethyl)benzothiazol-2-yl)methyl)-1-pyridazineacetic acid [MeSH Supplementary Concept]
- 3,4-dihydro-4-oxo-5,6-dimethyl-3-((5,7-difluorobenzothiazol-2-yl)methyl)-1-pyridazineacetic acid [MeSH Supplementary Concept]
- 3,4-dihydro-6-methoxy-3,7-dimethyl-1H-benzopyran-8-ol [MeSH Supplementary Concept]
- 3-((5-chlorobenzothiazol-2-yl)methyl)-1,2,3,4-tetrahydro-2,4-dioxopyrimidine-1-acetic acid [MeSH Supplementary Concept]
- 3-methyl-4-(4-chlorophenyl)isoxazolo(3,4-d)pyridazin-7(6H)-one acetic acid [MeSH Supplementary Concept]
- 35-kDa hypertonic stress protein, human [MeSH Supplementary Concept]
- 4-oxo-4-(4-hydroxyindole)butanoic acid [MeSH Supplementary Concept]
- 5-azidoalrestatin [MeSH Supplementary Concept]
- 5-isothiocyanatoalrestatin [MeSH Supplementary Concept]
- 6'-chloro-3'-methylspiro(imidazolidine-4,4'(1'H)-quinazoline)-2,2',5(3'H)-trione [MeSH Supplementary Concept]
- 6-(5-chloro-3-methylbenzofuran-2-sulfonyl)-2H-pyridazin-3-one [MeSH Supplementary Concept]
- 7-chloro-6-fluoro-4-hydroxy-2-methylchroman-4-acetic acid [MeSH Supplementary Concept]
- 7-dimethylsulfamoylxanthone-2-carboxylic acid [MeSH Supplementary Concept]
- 7-hydroxy-4-oxo-4H-chromen-2-carboxylic acid [MeSH Supplementary Concept]
- AD 5467 [MeSH Supplementary Concept]
- ADN 138 [MeSH Supplementary Concept]
- AL 3152 [MeSH Supplementary Concept]
- AL 4114 [MeSH Supplementary Concept]
- BAL-ARI8 [MeSH Supplementary Concept]
- FR 62765 [MeSH Supplementary Concept]
- FR 74366 [MeSH Supplementary Concept]
- GP 1447 [MeSH Supplementary Concept]
- ICI 105552 [MeSH Supplementary Concept]
- ICI 222155 [MeSH Supplementary Concept]
- IDD 393 [MeSH Supplementary Concept]
- IDD384 [MeSH Supplementary Concept]
- M 16209 [MeSH Supplementary Concept]
- M 16287 [MeSH Supplementary Concept]
- M 79175 [MeSH Supplementary Concept]
- N-(((4-benzoylamino)phenyl)sulfonyl)glycine [MeSH Supplementary Concept]
- N-((2-fluoro-6-methoxy-5-(trifluoromethyl)-1-naphthalenyl)carbonyl)-N-(methoxycarbonyl)glycine [MeSH Supplementary Concept]
- N-((aminocarbonyl)methyl)-2-fluoro-6-methoxy-5-(trifluoromethyl)-1-naphthalenecarboxamide [MeSH Supplementary Concept]
- N-(3beta-hydroxyurs-12-en-28-oyl)-4-aminobutyric acid [MeSH Supplementary Concept]
- N2-(2-methylaminobenzoyl)tetrahydro-1H-pyrido(3,4-b)indol-1-one [MeSH Supplementary Concept]
- ONO 1 [MeSH Supplementary Concept]
- ONO 3 [MeSH Supplementary Concept]
- SPR 210 [MeSH Supplementary Concept]
- WF 2421 [MeSH Supplementary Concept]
- WF 3681 [MeSH Supplementary Concept]
- YUA001 [MeSH Supplementary Concept]
- ZENECA ZD 5522 [MeSH Supplementary Concept]
- alconil [MeSH Supplementary Concept]
- asperaldin [MeSH Supplementary Concept]
- benzyl 5-phenyl-2-oxazolecarbamate [MeSH Supplementary Concept]
- cyano(5-fluoro-1-(4-methylbenzyl)-2-oxo-2,3-dihydroindol-3-yl)acetic acid [MeSH Supplementary Concept]
- danshenol A [MeSH Supplementary Concept]
- danshenol B [MeSH Supplementary Concept]
- dehydrocorydalin [MeSH Supplementary Concept]
- dihydrocitrinin [MeSH Supplementary Concept]
- ethyl 1-benzyl-3-hydroxy-2(5H)-oxopyrrole-4-carboxylate [MeSH Supplementary Concept]
- eutigoside B [MeSH Supplementary Concept]
- fidarestat [MeSH Supplementary Concept]
- ganoderic acid C2 [MeSH Supplementary Concept]
- glucodistylin [MeSH Supplementary Concept]
- gosha-jinki-gan-ryo extract [MeSH Supplementary Concept]
- idd 594 [MeSH Supplementary Concept]
- imirestat [MeSH Supplementary Concept]
- isodibut [MeSH Supplementary Concept]
- isoliquiritigenin [MeSH Supplementary Concept]
- kikkanol A [MeSH Supplementary Concept]
- kikkanol B [MeSH Supplementary Concept]
- kikkanol C [MeSH Supplementary Concept]
- kotalagenin 16-acetate [MeSH Supplementary Concept]
- lidorestat [MeSH Supplementary Concept]
- maleic acid [MeSH Supplementary Concept]
- matteuorienate A [MeSH Supplementary Concept]
- matteuorienate B [MeSH Supplementary Concept]
- minalrestat [MeSH Supplementary Concept]
- patuletin [MeSH Supplementary Concept]
- ponalrestat [MeSH Supplementary Concept]
- quercetagetin [MeSH Supplementary Concept]
- ranirestat [MeSH Supplementary Concept]
- rosmarinic acid [MeSH Supplementary Concept]
- salviaflaside [MeSH Supplementary Concept]
- salvianolic acid B [MeSH Supplementary Concept]
- salvianolic acid B [MeSH Supplementary Concept]
- salvianolic acid K [MeSH Supplementary Concept]
- semilicoisoflavone B [MeSH Supplementary Concept]
- sorbinil [MeSH Supplementary Concept]
- spirofluorene-9,5'-imidazolidine-2',4'-dione [MeSH Supplementary Concept]
- succinic acid benzyl ester 3-carboxymethyl-1-(4-chlorobenzoyl)-2-methylindol-5-yl ester [MeSH Supplementary Concept]
- tetra(hydroxyethyl)rutoside [MeSH Supplementary Concept]
- tetramethylene glutaric acid [MeSH Supplementary Concept]
- tolrestat [MeSH Supplementary Concept]
- zopolrestat [MeSH Supplementary Concept]
Record concept(s)
- aldehyde reductase [MeSH concept]
- aldose reductase ia [MeSH concept]
- aldose reductase ib [MeSH concept]
- erythrose reductase [MeSH concept]
- xylose reductase [MeSH concept]
Related MeSH Supplementary Concept(s)
- AKR1A1 protein, human [MeSH Supplementary Concept]
- AKR1B1 protein, human [MeSH Supplementary Concept]
- AKR1B10 protein, human [MeSH Supplementary Concept]
- AKR7A1 [MeSH Supplementary Concept]
- AKR7A3 protein, human [MeSH Supplementary Concept]
- Akr1a1 protein, mouse [MeSH Supplementary Concept]
- Akr1b1 protein, rat [MeSH Supplementary Concept]
- Akr1b10 protein, rat [MeSH Supplementary Concept]
- Akr1b3 protein, mouse [MeSH Supplementary Concept]
- Akr1b7 protein, mouse [MeSH Supplementary Concept]
- Akr1b7 protein, rat [MeSH Supplementary Concept]
- Akr1b8 protein, rat [MeSH Supplementary Concept]
- Akr1c14 protein, rat [MeSH Supplementary Concept]
- Ari1 protein, S cerevisiae [MeSH Supplementary Concept]
- WAY 121-509 [MeSH Supplementary Concept]
- YDR541C protein, S cerevisiae [MeSH Supplementary Concept]
- YGL039W protein, S cerevisiae [MeSH Supplementary Concept]
- YqhD protein, E coli [MeSH Supplementary Concept]
- aflatoxin B1 aldehyde reductase [MeSH Supplementary Concept]
- aldo-keto reductase family 1, member C14 protein, mouse [MeSH Supplementary Concept]
- androgen-inducible aldehyde reductase [MeSH Supplementary Concept]
- furfural reductase, E coli [MeSH Supplementary Concept]
- polyol dehydrogenase (NADP) [MeSH Supplementary Concept]
- renal-specific oxidoreductase, mouse [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- Aldehyde reductase (substance) [SNOMED CT concept]
- aldehyde reductase [SNOMED Notion]

Keyword's position in hierarchy(ies) :

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