Preferred Label : Anti-CD20 Monoclonal Antibody-FITC;
NCIt synonyms : Anti-CD20-Fluorescein Isothiocyanate; CD20-FITC; Anti-CD20-FITC;
NCIt definition : An immunoconjugate composed of a monoclonal antibody directed against the human antigen
CD20 that is conjugated to the fluorescein derivative and fluorochrome fluorescein
isothiocyanate (FITC), with potential use for imaging and detection of CD20-expressing
cells. Upon application of anti-CD20-FITC to a cell preparation, anti-CD20-FITC targets
and binds to CD20-expressing cells. Then, CD20-expressing cells in the sample can
be imaged using fluorescence-based imaging techniques or separated from other cells
present in the preparation using fluorescence-activated cell sorting (FACS). CD20
is a non-glycosylated cell surface phosphoprotein that is exclusively expressed on
B-cells during most stages of B-cell development; it is involved in the regulation
of B-cell differentiation and is overexpressed on certain types of cancer cells.;
NCI Metathesaurus CUI : CL521706;
Origin ID : C133777;
UMLS CUI : C4524885;
Semantic type(s)
- has_target
