Rough Endoplasmic Reticulum

Preferred Label : Rough Endoplasmic Reticulum;

NCIt synonyms : rER; Granular Endoplasmic Reticulum; Ergastoplasm; Rough-Surfaced Endoplasmic Reticulum; Rough ER;

NCIt definition : Membrane organelle of eukaryotes that forms sheets and tubules. Contains the receptor for the signal receptor particle and binds ribosomes engaged in translating mRNA for secreted proteins and the majority of transmembrane proteins. Also a site of membrane lipid synthesis. The membrane is very similar to the nuclear outer membrane. The lumen contains a number of proteins that possess the C terminal signal KDEL.;

Details

Origin ID

C13329;

UMLS CUI

C0230779;

Anatomic structure is physical part of
- Cell [NCIt concept]
Associated anatomy of gene products
- 39S Ribosomal Protein L45, Mitochondrial [NCIt concept]
- 40S Ribosomal Protein S10 [NCIt concept]
- 40S Ribosomal Protein S14 [NCIt concept]
- 40S Ribosomal Protein S15 [NCIt concept]
- 40S Ribosomal Protein S17 [NCIt concept]
- 40S Ribosomal Protein S19 [NCIt concept]
- 40S Ribosomal Protein S2 [NCIt concept]
- 40S Ribosomal Protein S20 [NCIt concept]
- 40S Ribosomal Protein S24 [NCIt concept]
- 40S Ribosomal Protein S26 [NCIt concept]
- 40S Ribosomal Protein S27 [NCIt concept]
- 40S Ribosomal Protein S3 [NCIt concept]
- 40S Ribosomal Protein S6 [NCIt concept]
- 40S Ribosomal Protein S7 [NCIt concept]
- 40S Ribosomal Protein SA [NCIt concept]
- 60S Acidic Ribosomal Protein P0 [NCIt concept]
- 60S Ribosomal Protein L10 [NCIt concept]
- 60S Ribosomal Protein L11 [NCIt concept]
- 60S Ribosomal Protein L13 [NCIt concept]
- 60S Ribosomal Protein L13a [NCIt concept]
- 60S Ribosomal Protein L19 [NCIt concept]
- 60S Ribosomal Protein L22 [NCIt concept]
- 60S Ribosomal Protein L26 [NCIt concept]
- 60S Ribosomal Protein L29 [NCIt concept]
- 60S Ribosomal Protein L35a [NCIt concept]
- 60S Ribosomal Protein L5 [NCIt concept]
- 60S Ribosomal Protein L7a [NCIt concept]
- 60S Ribosomal Protein L8 [NCIt concept]
- Alpha-2-Macroglobulin Receptor-Associated Protein [NCIt concept]
- Ribitol 5-Phosphate Transferase FKRP [NCIt concept]
- Ribosomal P Protein [NCIt concept]
- Ribosomal Protein [NCIt concept]
Automatic exact mappings (from CISMeF team)
- Agranular endoplasmic reticulum (cell structure) [SNOMED CT concept]
- endoplasmic reticulum [MeSH Descriptor]
- endoplasmic reticulum [MeSH concept]
Contains anatomical structure(s)
- Cisterna of the Rough Endoplasmic Reticulum [NCIt concept]
- Free Ribosome [NCIt concept]
- Membrane of the Rough Endoplasmic Reticulum [NCIt concept]
- Membrane-Attached Polyribosome [NCIt concept]
- Membrane-Attached Ribosome [NCIt concept]
- Ribosome [NCIt concept]
Currated CISMeF NLP mapping
- endoplasmic reticulum, rough [MeSH Descriptor]
- endoplasmic reticulum, rough [MeSH concept]
False automatic mappings
- Granular endoplasmic reticulum (cell structure) [SNOMED CT concept]
- Rough endoplasmic reticulum [FMA entity]
- granular endoplasmic reticulum, nos [SNOMED Notion]
- rough endoplasmic reticulum [GO term]
Semantic type(s)
- Cell Component [UMLS semantic type]
UMLS correspondences (same concept)
- Granular endoplasmic reticulum (cell structure) [SNOMED CT concept]
- Rough endoplasmic reticulum [FMA entity]
- endoplasmic reticulum, rough [MeSH concept]
- endoplasmic reticulum, rough [MeSH Descriptor]
- granular endoplasmic reticulum, nos [SNOMED Notion]
- rough endoplasmic reticulum [GO term]
anatomic_structure_has_location
- Cytoplasm [NCIt concept]

Keyword's position in hierarchy(ies) :

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