Preferred Label : Mcl-1 Inhibitor MIK665;
NCIt related terms : MIK-665;
NCIt definition : An inhibitor of induced myeloid leukemia cell differentiation protein (Mcl-1; Bcl2-L-3),
with potential pro-apoptotic and antineoplastic activities. Upon administration, MIK665
binds to and inhibits the activity of Mcl-1, which promotes apoptosis of cells overexpressing
Mcl-1. Mcl-1, an anti-apoptotic protein belonging to the Bcl-2 family of proteins,
is upregulated in cancer cells and promotes tumor cell survival.;
UNII : 801XYWHNOS;
InChIKey : NHDQXHYUSYRVEI-LDLOPFEMSA-N;
CAS number : 1799638-19-9;
Molecule name : MIK-665; MIK 665; S-64315; S 64315;
NCI Metathesaurus CUI : CL520448;
Origin ID : C133174;
UMLS CUI : C4524446;
Semantic type(s)
- concept_is_in_subset
- has_target
