Preferred Label : Z-DNA;
NCIt synonyms : zDNA;
NCIt definition : Z-DNA can be obtained for certain sequences such as CGCGCG by increasing the salt
concentration of the solution containing the sample to 4 molar NaCl. Z-DNA is left-handed
and the thinnest & tallest with a diameter of about 18 Angstrom. The sugar pucker
is both C(3')-endo and C(2')-endo. In Z-DNA, the Watson-Crick base pairs are perpendicular
to the helix axis. When examined from the top of the helix, bases are present throughout
the matrix of the helix with no exclusive domains for either the bases or the backbone.
At times the sugar phosphate backbone travels very close to the center of the helix,
and the bases to the very edge of the helix.;
Origin ID : C13287;
UMLS CUI : C0043442;
Automatic exact mappings (from CISMeF team)
- Semantic type(s)
- UMLS correspondences (same concept)
