Nisevokitug - CISMeF

Preferred Label : Nisevokitug;

NCIt synonyms : Anti-TGF-beta Monoclonal Antibody NIS793;

NCIt definition : A monoclonal antibody directed against human transforming growth factor beta (TGF-beta), with potential antineoplastic activity. Upon administration, nisevokitug targets and binds to TGF-beta, thereby preventing the activation of TGF-beta-mediated signaling pathways. TGF-beta, a pro-inflammatory mediator that is mutated and/or overexpressed in a number of cancer cell types, is involved in cancer cell proliferation and migration, and tumor progression.;

UNII : W2OR26S7UE;

CAS number : 2649854-92-0;

Molecule name : NIS793;

NCI Metathesaurus CUI : CL520460;

Details

Origin ID

C132250;

UMLS CUI

C5706630;

Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Immunologic Factor [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
chemical_or_drug_has_mechanism_of_action
- Antigen Binding [NCIt concept]
concept_is_in_subset
- CTRP Agent Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- GDC Terminology [NCIt concept]
- GDC Therapeutic Agent Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
- NCIt Antineoplastic Agent Terminology [NCIt concept]
has_target
- Transforming Growth Factor-Beta Superfamily [NCIt concept]

Keyword's position in hierarchy(ies) :

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