Dibotermin Alfa

Preferred Label : Dibotermin Alfa;

NCIt synonyms : rhBMP2; Diotermin;

NCIt definition : A recombinant form of human bone morphogenetic protein 2 (rhBMP-2), with potential bone remodeling and osteoinductive activities. Following administration, dibotermin alfa induces signaling cascades, which leads to osteoblast differentiation, enhancement of bone repair and formation, and improvement of re-vascularization. This promotes bone healing. BMP-2, a protein belonging to the transforming growth factor beta (TGFb) superfamily of proteins, plays a key role in bone and cartilage formation.;

UNII : T472P45MG6;

CAS number : 246539-15-1;

Molecule name : rhBMP-2;

Details

Origin ID

C132249;

UMLS CUI

C1445578;

Currated CISMeF NLP mapping
- Dibotermin alfa [ICD-11 Extension code]
- Dibotermin alfa [SMS substance]
- Dibotermin alfa (substance) [SNOMED CT concept]
- recombinant human bone morphogenetic protein-2 [MeSH concept]
- recombinant human bone morphogenetic protein-2 [MeSH Supplementary Concept]
See also inter- (CISMeF)
- Product containing dibotermin alfa (medicinal product) [SNOMED CT concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Dibotermin alfa (substance) [SNOMED CT concept]
- Product containing dibotermin alfa (medicinal product) [SNOMED CT concept]
- dibotermin alfa [ATC Code]
- recombinant human bone morphogenetic protein-2 [MeSH Supplementary Concept]
- recombinant human bone morphogenetic protein-2 [MeSH concept]
Validated automatic mappings to BTNT
- dibotermin alfa [ATC Code]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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