Preferred Label : Vidoflufolastat (18F);
NCIt synonyms : 18F-CTT1057; Fluorine F 18 CTT1057; 18F-CTT-1057; CTT 1057 18F; Fluorine-18-CTT 1057; CTT 1057 F18; PSMA-targeted PET Imaging Agent Fluorine F 18 CTT-1057;
NCIt definition : A radioconjugate composed of the phosphoramidate agent vidoflufolastat, a human prostate
specific membrane antigen (PSMA) inhibitor, and labeled with the radioisotope fluorine
F 18, with potential use as a tracer for PSMA-expressing tumors during positron emission
tomography (PET). Upon intravenous administration, vidoflufolastat (18F) targets and
irreversibly binds to the extracellular domain of PSMA-expressing tumor cells. Upon
rapid internalization, and following PET imaging, PSMA-expressing tumor cells can
be detected. PSMA, a tumor-associated antigen (TAA) and type II transmembrane protein,
is expressed on the membrane of prostatic epithelial cells and overexpressed on prostate
tumor cells.;
UNII : GA4V050P3M;
CAS number : 1628717-59-8; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 1628717-59-8
alt lien vers site G-SRS target _blank img src /img/logos/logo_g-srs.png alt Logo
G-SRS /a ;
NCI Metathesaurus CUI : CL520372;
Origin ID : C132028;
UMLS CUI : C5783367;
Semantic type(s)
- concept_is_in_subset
- has_target
