Preferred Label : Iodine I 131 MIP-1095;
NCIt synonyms : (131) I-MIP-1095; ((S)-2-(3-((S)-1-carboxy-5-(3-(4-[(131)I]iodophenyl)ureido)pentyl)ureido)pentanedioic
Acid; 131I-MIP-1095; I-131 MIP-1095;
NCIt related terms : MIP-1095 I-131;
NCIt definition : A radioconjugate composed of MIP-1095, a urea-based ligand for the tumor-associated
antigen (TAA) prostate-specific membrane antigen (PSMA) radiolabeled with iodine I
131 (I131), with potential antineoplastic activity. Upon administration of iodine
I 131 MIP-1095, the MIP-1095 moiety selectively targets and binds to the extracellular
domain of PSMA, thereby delivering cytotoxic iodine I 131 specifically to PSMA-expressing
cancer cells. PSMA is a transmembrane glycoprotein that is highly expressed by malignant
prostate epithelial cells and certain other tumor cells.;
UNII : 7DM27RQ9V0;
InChIKey : LFEGKCKGGNXWDV-LUOJOMRDSA-N;
CAS number : 1258980-67-4; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 1258980-67-4
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G-SRS /a ;
NCI Metathesaurus CUI : CL514422;
Origin ID : C131821;
UMLS CUI : C4330498;
Semantic type(s)
- concept_is_in_subset
- has_target
