" /> Anti-PD-L1 Monoclonal Antibody FAZ053 - CISMeF





Preferred Label : Anti-PD-L1 Monoclonal Antibody FAZ053;

NCIt related terms : FAZ-053;

NCIt definition : A monoclonal antibody directed against programmed cell death-1 ligand 1 (PD-L1), with immune checkpoint inhibitory and potential antineoplastic activities. Upon administration, anti-PD-L1 monoclonal antibody FAZ053 binds to PD-L1, blocking its binding to and activation of its receptor programmed death 1 (PD-1), which may enhance the T-cell-mediated anti-tumor immune response and reverse T-cell inactivation. PD-L1 is overexpressed by many human cancer cell types. PD-L1 binding to PD-1 on T-cells suppresses the immune system and results in immune evasion. PD-1, a transmembrane protein expressed on activated T-cells, is a negative regulator of the immune system that limits the expansion and survival of CD8 T-cells.;

UNII : V6W1OW12H2;

Molecule name : FAZ 053; FAZ-053;

NCI Metathesaurus CUI : CL514246;

Details


You can consult :


Nous contacter.
09/05/2025


[Home] [Top]

© Rouen University Hospital. Any partial or total use of this material must mention the source.