Multiple TAA-loaded Dendritic Cell Vaccine

Preferred Label : Multiple TAA-loaded Dendritic Cell Vaccine;

NCIt synonyms : MASCT-I; Multiple Target Antigen-stimulating Cells-I; Multiple TAA-loaded DC Vaccine; Antigen-pulsed DCs MASCT-I;

NCIt definition : A dendritic cell (DC) vaccine in which autologous DCs are loaded with multiple tumor-associated antigens (TAAs), with potential immunostimulating and antineoplastic activities. Upon re-infusion into the patient, the antigen-pulsed DCs stimulate the immune system to mount a specific cytotoxic T-lymphocyte (CTL) response against the TAA-expressing tumor cells.;

NCI Metathesaurus CUI : CL514420;

Details

Origin ID

C131336;

UMLS CUI

C4330723;

Semantic type(s)
- Immunologic Factor [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
chemical_or_drug_affects_cell_type_or_tissue
- Cytotoxic T-Lymphocyte [NCIt concept]
chemical_or_drug_has_mechanism_of_action
- Antigen Sensitization [NCIt concept]
chemical_or_drug_has_physiologic_effect
- Immunopotentiation [NCIt concept]
- T-Cell Activation [NCIt concept]
concept_is_in_subset
- NCI Drug Dictionary Terminology [NCIt concept]
- NCIt Antineoplastic Agent Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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