ZFTA/RELA Fusion Gene

Preferred Label : ZFTA/RELA Fusion Gene;

NCIt synonyms : C11orf95-RELA Fusion Gene; ZFTA-RELA Fusion Gene; C11orf95/RELA Fusion Gene; ZFTA::RELA Fusion Gene;

NCIt definition : A fusion gene that results from chromothripsis involving chromosome 11q13.1, which fuses the first 2, 3 or 4 exons of the ZFTA gene to sequences that are located 5' of either exon 2 or 3 of the RELA gene. This rearrangement is associated with supratentorial ependymoma.;

PubMed : 24553141;

Details

Origin ID

C129353;

UMLS CUI

C3810323;

Automatic exact mappings (from CISMeF team)
- Rela protooncogene, nfkb subunit [OMIM gene]
- Zinc finger translocation-associated protein [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
gene_encodes_gene_product
- ZFTA/RELA Fusion Protein [NCIt concept]
gene_involved_in_molecular_abnormality
- ZFTA-RELA Fusion Protein Expression [NCIt concept]
gene_involved_in_pathogenesis_of_disease
- Supratentorial Ependymoma, ZFTA-RELA Fusion-Positive [NCIt concept]
gene_mapped_to_disease
- Supratentorial Ependymoma, ZFTA-RELA Fusion-Positive [NCIt concept]
related_to_genetic_biomarker
- RELA Gene [NCIt concept]
- ZFTA Gene [NCIt concept]

Keyword's position in hierarchy(ies) :

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