Astrocytoma, IDH-Mutant, Grade 3

Preferred Label : Astrocytoma, IDH-Mutant, Grade 3;

NCIt synonyms : Astrocytoma, IDH-Mutant, Grade III; Anaplastic Astrocytoma, IDH-Mutant;

NCIt related terms : Anaplastic Astrocytoma, IDH Mutant;

NCIt definition : IDH-mutant astrocytoma characterized by the presence of increased mitotic activity and anaplastic features.;

Neoplastic status : Malignant;

NCI Metathesaurus CUI : CL512333;

Details

Origin ID

C129290;

UMLS CUI

C4289981;

Automatic exact mappings (from CISMeF team)
- Astrocytoma, anaplastic, IDH-mutant [ICD-11 Extension code]
- IDH-mutant anaplastic astrocytoma [DO Concept]
Disease may have findings
- Headache [NCIt concept]
- Motor Manifestations [NCIt concept]
- Seizure [NCIt concept]
- Sensory Manifestations [NCIt concept]
- Unfavorable Clinical Outcome [NCIt concept]
Has associated anatomic sites
- Central Nervous System [NCIt concept]
- Nervous System [NCIt concept]
Semantic type(s)
- Neoplastic Process [UMLS semantic type]
concept_is_in_subset
- CPTAC Baseline Medical Forms Terminology [NCIt concept]
- CPTAC Brain Lower Grade Glioma Baseline Form [NCIt concept]
- CPTAC Terminology [NCIt concept]
- GDC Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
- NCIt Neoplasm Core Terminology [NCIt concept]
disease_excludes_finding
- Benign Cellular Infiltrate [NCIt concept]
- Grade 4 Lesion [NCIt concept]
- Indolent Clinical Course [NCIt concept]
- Microvascular Proliferation [NCIt concept]
- Necrotic Change [NCIt concept]
- Precise Histogenesis Unknown [NCIt concept]
disease_excludes_molecular_abnormality
- 1p/19q Codeletion [NCIt concept]
disease_has_abnormal_cell
- Anaplastic Astrocyte [NCIt concept]
- Malignant Cell [NCIt concept]
- Neoplastic Astrocyte [NCIt concept]
- Neoplastic Cell [NCIt concept]
- Neoplastic Glial Cell [NCIt concept]
- Neoplastic Neuroepithelial Cell [NCIt concept]
- Neoplastic Neuroepithelial Cell and Neoplastic Perineural Cell [NCIt concept]
disease_has_finding
- Anaplastic Lesion [NCIt concept]
- Diffuse Pattern [NCIt concept]
- High Grade Lesion [NCIt concept]
- Increased Cellularity Present [NCIt concept]
- Infiltrative Growth Pattern [NCIt concept]
- Malignant Cellular Infiltrate [NCIt concept]
- Mitotic Activity [NCIt concept]
- Nuclear Atypia [NCIt concept]
disease_has_grade
- Grade 3 [NCIt concept]
- High Grade [NCIt concept]
disease_has_molecular_abnormality
- IDH Gene Family Mutation [NCIt concept]
disease_has_normal_cell_origin
- Astrocyte [NCIt concept]
- Glial Cell [NCIt concept]
- Neuroepithelial Cell [NCIt concept]
- Neuron, Neuroepithelial Cell, and Supporting Cell of the Nervous System [NCIt concept]
disease_has_normal_tissue_origin
- Nerve Tissue, Neuroepithelial Tissue, and Nerve Sheaths [NCIt concept]
- Neuroepithelial Tissue [NCIt concept]
disease_has_primary_anatomic_site
- Central Nervous System [NCIt concept]
disease_mapped_to_gene
- IDH Gene Family [NCIt concept]
- TP53 Gene [NCIt concept]
disease_may_have_cytogenetic_abnormality
- Loss of Chromosome 6 [NCIt concept]
disease_may_have_molecular_abnormality
- CDKN2A Gene Deletion [NCIt concept]
- PTEN Gene Inactivation [NCIt concept]
- RB1 Gene Inactivation [NCIt concept]
- TP53 Gene Inactivation [NCIt concept]

Keyword's position in hierarchy(ies) :

You can consult :

recommendations
documents concerning education
documents for patients