NCIt synonyms : Gene Expression Inhibitor; Antisense Agents; AS ODNs;
NCIt related terms : antisense oligonucleotide; antisense agent;
NCIt definition : Antisense Oligonucleotides, short synthetic segments of DNA or RNA, designed with
a sequence complimentary to a specific mRNA that target and bind with mRNA, causing
inhibition of translation or overexpression of the protein encoded by the mRNA.;
Alternative definition : NCI-GLOSS: Small pieces of DNA or RNA that can bind to specific molecules of RNA.
This blocks the ability of the RNA to make a protein or work in other ways. Antisense
agents may be used to block the production of proteins needed for cell growth. They
are being studied in the treatment of several types of cancer.;
Codes from synonyms : CDR0000488672; CDR0000649024;
Currated CISMeF NLP mapping