Antisense Oligonucleotides

Preferred Label : Antisense Oligonucleotides;

NCIt synonyms : Gene Expression Inhibitor; Antisense Agents; AS ODNs;

NCIt related terms : antisense oligonucleotide; antisense agent;

NCIt definition : Antisense Oligonucleotides, short synthetic segments of DNA or RNA, designed with a sequence complimentary to a specific mRNA that target and bind with mRNA, causing inhibition of translation or overexpression of the protein encoded by the mRNA.;

Alternative definition : NCI-GLOSS: Small pieces of DNA or RNA that can bind to specific molecules of RNA. This blocks the ability of the RNA to make a protein or work in other ways. Antisense agents may be used to block the production of proteins needed for cell growth. They are being studied in the treatment of several types of cancer.;

Codes from synonyms : CDR0000488672; CDR0000649024;

Détails

Origin ID

C1291;

UMLS CUI

C0079925;

Currated CISMeF NLP mapping
- Antisense oligonucleotide (substance) [SNOMED CT concept]
- oligonucleotides, antisense [MeSH Descriptor]
- oligonucleotides, antisense [MeSH concept]
Semantic type(s)
- Biologically Active Substance [UMLS semantic type]
- Indicator, Reagent, or Diagnostic Aid [UMLS semantic type]
- Nucleic Acid, Nucleoside, or Nucleotide [UMLS semantic type]
UMLS correspondences (same concept)
- Antisense oligonucleotide (substance) [SNOMED CT concept]
- oligonucleotides, antisense [MeSH Descriptor]
- oligonucleotides, antisense [MeSH concept]
concept_is_in_subset
- NCI Drug Dictionary Terminology [NCIt concept]

Position du mot-clé dans l'(les) arborescence(s) :

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