5-Methylcytosine

Preferred Label : 5-Methylcytosine;

NCIt definition : A methylated form of the nucleobase cytosine occurring predominantly in cytosine-phosphate-guanine (CpG) islands that are produced by DNA methyltransferases and may regulate gene expression. Like cytosine, the DNA sequence containing 5-methylcytosine (5-mC) is able to be replicated without error and 5-mC can pair with guanine in double stranded DNA. However, DNA sequences containing a high local concentration of 5-mC may be less transcriptionally active than areas with higher ratios of unmodified cytosine.;

UNII : 6R795CQT4H;

InChIKey : LRSASMSXMSNRBT-UHFFFAOYSA-N;

CAS number : 554-01-8;

ChEBI ID : CHEBI:27551;

Details

Origin ID

C129008;

UMLS CUI

C0049308;

Automatic exact mappings (from CISMeF team)
- 5-Methylcytosine [MeSH concept]
- 5-methylcytosine [Substance BNPC]
- 5-methylcytosine [MeSH Descriptor]
Semantic type(s)
- Biologically Active Substance [UMLS semantic type]
- Nucleic Acid, Nucleoside, or Nucleotide [UMLS semantic type]
UMLS correspondences (same concept)
- 5-Methylcytosine [MeSH concept]
- 5-methylcytosine [Substance BNPC]
- 5-methylcytosine [MeSH Descriptor]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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