Multi-epitope Anti-folate Receptor Peptide Vaccine TPIV 200

Preferred Label : Multi-epitope Anti-folate Receptor Peptide Vaccine TPIV 200;

NCIt synonyms : TPIV 200 Vaccine; TPIV200/huFR-1;

NCIt definition : A peptide vaccine containing five immunogenic peptide epitopes of the human folate receptor 1 (FOLR1; FR-alpha), with potential immunomodulating and antineoplastic activities. Upon intradermal administration, multi-epitope anti-folate receptor peptide vaccine TPIV 200 may induce a cytotoxic T-lymphocyte (CTL) response against FR-alpha-overexpressing tumor cells. FR-alpha is a high-affinity folate-binding protein and a member of the folate receptor family; this receptor is overexpressed in various cancer cell types.;

Molecule name : TPIV-200; TPIV 200;

NCI Metathesaurus CUI : CL512164;

Details

Origin ID

C128898;

UMLS CUI

C4287699;

Automatic exact mappings (from CISMeF team)
- Microcephalic osteodysplastic primordial dwarfism types I and III [ORDO Disease]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Immunologic Factor [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
chemical_or_drug_has_mechanism_of_action
- Antigen Sensitization [NCIt concept]
concept_is_in_subset
- CTRP Agent Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- GDC Terminology [NCIt concept]
- GDC Therapeutic Agent Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
- NCIt Antineoplastic Agent Terminology [NCIt concept]
has_target
- Folate Receptor Alpha [NCIt concept]

Keyword's position in hierarchy(ies) :

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