Selective Estrogen Receptor Degrader LSZ102

Preferred Label : Selective Estrogen Receptor Degrader LSZ102;

NCIt synonyms : SERD LSZ102; SERD LSZ 102;

NCIt related terms : LSZ-102;

NCIt definition : An selective estrogen receptor (ER) degrader (SERD), with potential antineoplastic activity. Upon administration of LSZ102, this agent binds to the ER and induces the degradation of the receptor. This prevents ER activation and ER-mediated signaling, and inhibits the growth and survival of ER-expressing cancer cells.;

UNII : 0Y175XGX4P;

CAS number : 2135600-76-7;

Molecule name : LSZ 102; LSZ102;

NCI Metathesaurus CUI : CL507934;

Details

Origin ID

C128280;

UMLS CUI

C4287740;

Currated CISMeF NLP mapping
- LSZ102 [MeSH Supplementary Concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- LSZ102 [MeSH Supplementary Concept]
concept_is_in_subset
- CTRP Agent Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- GDC Terminology [NCIt concept]
- GDC Therapeutic Agent Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
- NCIt Antineoplastic Agent Terminology [NCIt concept]
has_target
- Estrogen Receptor [NCIt concept]

Keyword's position in hierarchy(ies) :

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