" /> PDGFRB NP_002600.1:p.T681I - CISMeF





Preferred Label : PDGFRB NP_002600.1:p.T681I;

NCIt synonyms : PDGFR-Beta T681I; PDGFR-Beta Thr681Ile; PDGFR-1 T681I; PDGFRB T681I; PDGFRB p.T681I; PDGFR-1 Thr681Ile; PDGFRB NP_002600.1:pThr681Ile; NP_002600.1:pT681I; PDGFRB Thr681Ile; PDGFRB p.Thr681Ile; NP_002600.1:pThr681Ile; Beta Platelet-Derived Growth Factor Receptor T681I; Beta Platelet-Derived Growth Factor Receptor Thr681Ile; CD140 Antigen-Like Family Member B T681I; PDGF-R-Beta T681I; CD140 Antigen-Like Family Member B Thr681Ile; PDGF-R-Beta Thr681Ile; Platelet-Derived Growth Factor Receptor 1 T681I; Platelet-Derived Growth Factor Receptor Beta T681I; Platelet-Derived Growth Factor Receptor 1 Thr681Ile; Platelet-Derived Growth Factor Receptor Beta Thr681Ile; CD140b T681I; Beta-Type Platelet-Derived Growth Factor Receptor T681I; Beta-Type Platelet-Derived Growth Factor Receptor Thr681Ile; CD140b Thr681Ile;

NCIt definition : A change in the amino acid residue at position 681 in the platelet-derived growth factor receptor beta protein where threonine has been replaced by isoleucine.;

NCIt note : This amino acid variation is located in the kinase domain (KD) of platelet-derived growth factor receptor beta (PDGFRB). Tumors expressing this PDGFRB protein variant or fusion proteins containing this PDGFRB KD variation may be resistant to imatinib and dasatinib.;

NCI Metathesaurus CUI : CL508923;

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12/05/2024


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