" /> Vinorelbine - CISMeF





Preferred Label : Vinorelbine;

NCIt synonyms : Dihydroxydeoxynorvinkaleukoblastine; 3',4'-Didehydro-4'-deoxy-C'-norvincaleukoblastine; 5'-Nor-Anhydrovinblastine; nor-5'-Anhydrovinblastine;

NCIt definition : A semisynthetic vinca alkaloid. Vinorelbine binds to tubulin and prevents formation of the mitotic spindle, resulting in the arrest of tumor cell growth in metaphase. This agent may also interfere with amino acid, cyclic AMP. and glutathione metabolism; calmodulin-dependent Ca -transport ATPase activity; cellular respiration; and nucleic acid and lipid biosynthesis.;

Alternative definition : NCI-GLOSS: An anticancer drug that belongs to the family of plant drugs called vinca alkaloids.;

UNII : Q6C979R91Y;

InChIKey : GBABOYUKABKIAF-IELIFDKJSA-N;

CAS number : 71486-22-1; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 71486-22-1 alt lien vers site G-SRS target _blank img src /img/logos/logo_g-srs.png alt Logo G-SRS /a ;

Chemical formula : C45H54N4O8;

ChEBI ID : CHEBI:480999;

Codes from synonyms : CDR0000045299; 540;

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15/05/2024


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