ME1 wt Allele - CISMeF

Preferred Label : ME1 wt Allele;

NCIt synonyms : Malate Dehydrogenase, NADP( )-Dependent, Soluble Gene; HUMNDME; Malic Enzyme, Cytoplasmic Gene; Malic Enzyme 1, Soluble Gene; Malate Dehydrogenase (Oxaloacetate-Decarboxylating) (NADP( )) Gene; Malic Enzyme 1, NADP( )-Dependent, Cytosolic Gene; MES; Malic Enzyme 1 wt Allele; Malic Enzyme, NADP( )-Dependent, Cytosolic Gene;

NCIt definition : Human ME1 wild-type allele is located in the vicinity of 6q12 and is approximately 221 kb in length. This allele, which encodes NADP-dependent malic enzyme protein, is involved in glycolysis, the citric acid cycle and fatty acid biogenesis.;

NCI Metathesaurus CUI : CL508908;

GenBank Accession Number : X77244;

Details

Origin ID

C127140;

UMLS CUI

C4283758;

Automatic exact mappings (from CISMeF team)
- Malic enzyme 1 [OMIM gene]
- Meckel syndrome, type 1 [OMIM Phenotype]
OMIM relation
- Malic enzyme 1 [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_found_in_organism
- Human [NCIt concept]
gene_in_chromosomal_location
- 6q12 [NCIt concept]
gene_is_element_in_pathway
- Acetyl Group Shuttle Pathway [NCIt concept]
- PPAR Signaling Pathway [NCIt concept]
- PPAR-alpha Gene Regulation Pathway [NCIt concept]
- Pyruvate Metabolism Pathway [NCIt concept]
gene_plays_role_in_process
- Carbohydrate Metabolic Process [NCIt concept]
- Lipid Metabolic Process [NCIt concept]
- Nucleotide Biosynthesis Process [NCIt concept]
- Oxidation [NCIt concept]
- Oxidation/Reduction [NCIt concept]

Keyword's position in hierarchy(ies) :

You can consult :

recommendations
documents concerning education
documents for patients