" /> GPX3 wt Allele - CISMeF





Preferred Label : GPX3 wt Allele;

NCIt synonyms : Glutathione Peroxidase 3 (Plasma) Gene; GPx-P; Glutathione Peroxidase 3 wt Allele; GPXP; GSHPx-P; Glutathione Peroxidase 3, Plasma Gene; GSHPx-3;

NCIt definition : Human GPX3 wild-type allele is located 5q33.1 and is approximately 9 kb in length. This allele, which encodes glutathione peroxidase 3 protein, plays a role in hydrogen peroxide and lipid peroxide metabolism.;

NCIt note : The protein encoded by the GPX3 gene contains a selenocysteine residue, which is encoded by UGA. In order for the UGA codon to be translated as a selenocysteine rather than a stop codon, a stem-loop structure called a selenocysteine insertion sequence (SECIS) must be present in the 3' untranslated region (UTR) of the selenoprotein mRNA.;

NCI Metathesaurus CUI : CL508150;

GenBank Accession Number : NM_002084;

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20/05/2024


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