Keratin, Type II Cytoskeletal 8

Preferred Label : Keratin, Type II Cytoskeletal 8;

NCIt synonyms : K8; CK-8; Cytokeratin 8; Keratin-8; Type-II Keratin Kb8; Keratin 8; Cytokeratin-8; KRT8;

NCIt definition : Keratin, type II cytoskeletal 8 (483 aa, 54 kDa) is encoded by the human KRT8 gene. This protein is involved in maintaining the structure of striated muscles and simple epithelia.;

NCIt note : Keratin, type II cytoskeletal 8 interacts with keratin, type I cytoskeletal 19 in striated muscles and with keratin, type I cytoskeletal 18 in simple single-layered epithelial cells. (UniProt and EntrezGene);

Details

Origin ID

C126964;

UMLS CUI

C1432126;

Automatic exact mappings (from CISMeF team)
- Cytokeratin 8 [LOINC component]
- Keratin 8, type II [OMIM gene]
- Keratin-8 [MeSH Descriptor]
- Keratin-8 [MeSH concept]
- keratin 8 [HGNC gene]
OMIM relation
- Keratin 8, type II [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- KRT8 protein, human [MeSH Supplementary Concept]
- KRT8 protein, human [MeSH concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Cytoskeletal Gene [NCIt concept]
- Intermediate Filament Gene [NCIt concept]
- KRT8 Gene [NCIt concept]
- Structural Protein Gene [NCIt concept]
gene_product_has_associated_anatomy
- Cytoskeleton [NCIt concept]
- Intermediate Filament [NCIt concept]
- Keratin Filament [NCIt concept]
gene_product_has_biochemical_function
- Scaffolding Protein [NCIt concept]
gene_product_has_chemical_classification
- Cytokeratin [NCIt concept]
gene_product_plays_role_in_biological_process
- Cell Movement Process [NCIt concept]
- Cytoskeletal Modeling [NCIt concept]
- Cytoskeletal Process [NCIt concept]
- Keratinization [NCIt concept]
- Protein-Protein Interaction [NCIt concept]
- Regulation of Cell Shape [NCIt concept]

Keyword's position in hierarchy(ies) :

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