ROBO2 wt Allele

Preferred Label : ROBO2 wt Allele;

NCIt synonyms : SAX3, C. elegans, Homolog of, 2 Gene; Roundabout Guidance Receptor 2 wt Allele; Roundabout (Axon Guidance Receptor, Drosophila) Homolog 2 Gene; Roundabout, Drosophila, Homolog of, 2 Gene; KIAA1568; Roundabout, Axon Guidance Receptor, Homolog 2 Gene; SAX3; Roundabout, Axon Guidance Receptor, Homolog 2 (Drosophila) Gene;

NCIt definition : Human ROBO2 wild-type allele is located in the vicinity of 3p12.3 and is approximately 1743 kb in length. This allele, which encodes roundabout homolog 2 protein, is involved in axon guidance, cell migration and ligand binding. Chromosomal anomalies, including t(Y;3)(p11;p12), that cause dominant-negative mutations in this gene are associated with vesicoureteral reflux.;

NCI Metathesaurus CUI : CL508056;

GenBank Accession Number : AF040991;

Details

Origin ID

C126775;

UMLS CUI

C4284464;

Automatic exact mappings (from CISMeF team)
- Roundabout guidance receptor 2 [OMIM gene]
- roundabout guidance receptor 1 [ORDO Gene]
- roundabout guidance receptor 2 [ORDO Gene]
OMIM relation
- Roundabout guidance receptor 2 [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_found_in_organism
- Human [NCIt concept]
gene_is_element_in_pathway
- Axon Guidance Pathway [NCIt concept]
gene_plays_role_in_process
- Cellular Migration Process [NCIt concept]
- Ligand Binding [NCIt concept]
- Nervous System Development [NCIt concept]
- Neural Development [NCIt concept]
- Receptor Signaling [NCIt concept]

Keyword's position in hierarchy(ies) :

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