Triptorelin - CISMeF

Preferred Label : Triptorelin;

NCIt synonyms : Detryptoreline; 6-D-Tryptophanluteinizing Hormone-releasing Factor; 6-D-Tryptophan-LH-RH;

NCIt definition : A synthetic decapeptide agonist analog of luteinizing hormone releasing hormone (LHRH). Possessing greater potency than endogenous LHRH, triptorelin reversibly represses gonadotropin secretion. After chronic, continuous administration, this agent effects sustained decreases in LH and FSH production and testicular and ovarian steroidogenesis. Serum testosterone concentrations may fall to levels typically observed in surgically castrated men. (NCI04);

Alternative definition : NCI-GLOSS: A drug that is used to treat advanced prostate cancer, and is being studied in the treatment of breast cancer. It belongs to the family of hormonal drugs called gonadotropin-releasing hormone analogs.;

UNII : 9081Y98W2V;

CAS number : 57773-63-4;

Molecule name : AY-25650; CL-118,532; AY 25650; CL 118532; CL-118532;

Chemical formula : C64H82N18O13;

ChEBI ID : CHEBI:63633;

Codes from synonyms : CDR0000045769; 518;

Details

Origin ID

C1267;

UMLS CUI

C0077275;

See also inter- (CISMeF)
- Product containing triptorelin (medicinal product) [SNOMED CT concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Hormone [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Product containing triptorelin (medicinal product) [SNOMED CT concept]
- Triptorelin (substance) [SNOMED CT concept]
- triptorelin [ATC Code]
- triptorelin [MeSH concept]
Validated automatic mappings to BTNT
- triptorelin [ATC Code]
- triptorelin pamoate [MeSH Descriptor]
concept_is_in_subset
- CTRP Agent Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- GDC Terminology [NCIt concept]
- GDC Therapeutic Agent Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
- HemOnc Agent Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
- NCIt Antineoplastic Agent Terminology [NCIt concept]
- Operational Ontology for Radiation Oncology Prostate Cancer Terminology [NCIt concept]
has_salt_form
- Triptorelin Acetate [NCIt concept]
- Triptorelin Pamoate [NCIt concept]
has_target
- Gonadotropin-Releasing Hormone Receptor [NCIt concept]
is_component_of_chemotherapy_regimen
- Bicalutamide/Triptorelin Regimen [NCIt concept]
- Cyproterone/Triptorelin [NCIt concept]
- Exemestane/Triptorelin [NCIt concept]
- Flutamide/Triptorelin [NCIt concept]
- Nilutamide/Triptorelin [NCIt concept]
- Tamoxifen/Triptorelin [NCIt concept]
is_free_acid_or_base_form_of
- Triptorelin Acetate [NCIt concept]
- Triptorelin Pamoate [NCIt concept]

Keyword's position in hierarchy(ies) :

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