Met-Enkephalin

Preferred Label : Met-Enkephalin;

NCIt synonyms : OGF; YGGPM; [Met(5)]-Enkephalin; Opioid Growth Factor; Tyr-Gly-Gly-Phe-Met;

NCIt definition : Met-enkephalin (5 aa, 1 kDa) is encoded by the human PENK and POMC genes. This protein plays a role in the activation of delta opioid receptors.;

NCIt note : Proenkephalin-A has multiple sequences that can be cleaved to release Met-enkephalin, while pro-opiomelanocortin contains one Met-enkephalin peptide. (UniProt);

Details

Origin ID

C126497;

UMLS CUI

C5441703;

Currated CISMeF NLP mapping
- Met-enkephalin (substance) [SNOMED CT concept]
- enkephalin, methionine [MeSH Descriptor]
- enkephalin, methionine [MeSH concept]
- met-enkephalin [SNOMED Notion]
OMIM relation
- Proenkephalin [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Met-enkephalin (substance) [SNOMED CT concept]
- enkephalin, methionine [Substance BNPC]
- enkephalin, methionine [MeSH Descriptor]
- enkephalin, methionine [MeSH concept]
- met-enkephalin [SNOMED Notion]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- PENK Gene [NCIt concept]
- POMC Gene [NCIt concept]
- Peptide Hormone Gene [NCIt concept]
gene_product_has_associated_anatomy
- Extracellular Space [NCIt concept]
gene_product_has_biochemical_function
- Growth Factor [NCIt concept]
gene_product_plays_role_in_biological_process
- Intercellular Communication Process [NCIt concept]
- Nociception [NCIt concept]
- Receptor Signaling [NCIt concept]
- Signal Transduction [NCIt concept]

Keyword's position in hierarchy(ies) :

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