Chimeric Antigen Receptor T-Cell Therapy

Preferred Label : Chimeric Antigen Receptor T-Cell Therapy;

NCIt synonyms : CAR T-cell Therapy; CAR T Therapy; CAR T Infusion; Chimeric Antigen Receptor T-cell Infusion;

NCIt definition : Treatment that uses T-cells that have been engineered to contain a chimeric antigen receptor (CAR) that specifically targets a particular antigen.;

Alternative definition : NCI-GLOSS: A type of treatment in which a patient's T cells (a type of immune system cell) are changed in the laboratory so they will attack cancer cells. T cells are taken from a patient's blood. Then the gene for a special receptor that binds to a certain protein on the patient's cancer cells is added in the laboratory. The special receptor is called a chimeric antigen receptor (CAR). Large numbers of the CAR T cells are grown in the laboratory and given to the patient by infusion. Chimeric antigen receptor T-cell therapy is being studied in the treatment of some types of cancer.;

NCI Metathesaurus CUI : CL504697;

Codes from synonyms : CDR0000771302; CDR0000771301;

Details

Origin ID

C126102;

UMLS CUI

C4289797;

Automatic exact mappings (from CISMeF team)
- CAR T-cell therapy [MedDRA LLT]
- Chimeric antigen receptor T-cell therapy [MedDRA LLT]
- immunotherapy, adoptive [MeSH Descriptor]
Semantic type(s)
- Therapeutic or Preventive Procedure [UMLS semantic type]
UMLS correspondences (same concept)
- CAR T-cell therapy [MedDRA LLT]
- Chimeric antigen receptor T-cell therapy [MedDRA LLT]
concept_is_in_subset
- AML Authorized Value Terminology [NCIt concept]
- AML Cellular Immunotherapy Table [NCIt concept]
- CTRP Intervention Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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