Begelomab - CISMeF

Preferred Label : Begelomab;

NCIt synonyms : Begedina;

NCIt definition : A monoclonal antibody against the human dipeptidyl peptidase 4 (dipeptidylpeptidase IV, DPPIV, DPP4; CD26), with potential activity against graft-versus-host disease (GvHD). Upon administration, begelomab binds to CD26 expressed on T-cells. This inhibits the stimulation of T-cells and may prevent GvHD. CD26, a membrane-bound glycoprotein with dipeptidyl peptidase activity, plays a key role in T-cell activation and immune regulation.;

UNII : 360N6PY2A1;

CAS number : 1403744-56-8;

Molecule name : BT 5/9; SAND-26;

NCI Metathesaurus CUI : CL504312;

Details

Origin ID

C125608;

UMLS CUI

C4059170;

Currated CISMeF NLP mapping
- Begelomab [ICD-11 Extension code]
- Begelomab [SMS substance]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Immunologic Factor [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- begelomab [ATC Code]
Validated automatic mappings to BTNT
- begelomab [ATC Code]
chemical_or_drug_has_mechanism_of_action
- Antigen Binding [NCIt concept]
concept_is_in_subset
- CTRP Agent Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
has_target
- Dipeptidyl Peptidase 4 [NCIt concept]

Keyword's position in hierarchy(ies) :

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