P-cadherin-targeting Agent PF-06671008

Preferred Label : P-cadherin-targeting Agent PF-06671008;

NCIt related terms : PF-06671008;

NCIt definition : An agent that targets p-cadherin (CDH3), with potential antineoplastic activity. Upon administration, PF-06671008 binds to and inhibits the activity of p-cadherin; this may inhibit both invasion and proliferation of p-cadherin expressing tumor cells. P-cadherin, a cell-surface protein and member of the cadherin family, is overexpressed in a variety of tumors and plays a role in cell adhesion, motility, invasion, and proliferation.;

UNII : 2GWZ8HN70W;

Molecule name : PF-06671008;

NCI Metathesaurus CUI : CL504311;

Details

Origin ID

C125607;

UMLS CUI

C4086683;

Currated CISMeF NLP mapping
- PF-06671008 [MeSH Supplementary Concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- PF-06671008 [MeSH Supplementary Concept]
concept_is_in_subset
- CTRP Agent Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- GDC Terminology [NCIt concept]
- GDC Therapeutic Agent Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
- NCIt Antineoplastic Agent Terminology [NCIt concept]
has_target
- Cadherin-3 [NCIt concept]

Keyword's position in hierarchy(ies) :

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