Preferred Label : Bcl-2 Inhibitor BCL201;
NCIt related terms : S-55746;
NCIt definition : A selective inhibitor of the anti-apoptotic protein B-cell lymphoma 2 (Bcl-2), with
potential pro-apoptotic and antineoplastic activities. Upon administration, Bcl-2
inhibitor BCL201 binds to and inhibits the activity of Bcl-2. This restores apoptotic
processes in tumor cells. Bcl-2 protein is overexpressed in many cancers and plays
an important role in the negative regulation of apoptosis; its expression is associated
with increased drug resistance and tumor cell survival.;
UNII : W93257I68I;
CAS number : 1448584-12-0;
Molecule name : BCL-201; S-55746; Servier 1; Servier-1;
NCI Metathesaurus CUI : CL504308;
Origin ID : C125603;
UMLS CUI : C4086018;
Semantic type(s)
- concept_is_in_subset
- has_target
