Protachykinin-1

Preferred Label : Protachykinin-1;

NCIt synonyms : Protachykinin 1; PPT; Preprotachykinin; Protachykinin;

NCIt definition : Protachykinin-1 (129 aa, 15 kDa) is encoded by the human TAC1 gene. This protein is involved in neuronal excitation, behavioral responses, and smooth muscle contraction.;

NCIt note : Protachykinin-1 is cleaved into the following 7 biologically active peptide chains: Substance P, Neurokinin A (NKA, Neurokinin alpha), Neuromedin L, Substance K, Neuropeptide K (NPK), Neuropeptide gamma, and C-terminal-flanking peptide. (UniProt);

Details

Origin ID

C124856;

UMLS CUI

C4084848;

Automatic exact mappings (from CISMeF team)
- Palmitoyl-protein thioesterase 1 [OMIM gene]
- palmitoyl-protein thioesterase 1 [ORDO Gene]
- phosphoenolpyruvate:phosphate antiporter activity [GO term]
- polyphosphate:AMP phosphotransferase activity [GO term]
- preprotachykinin [MeSH concept]
- preprotachykinin [MeSH Supplementary Concept]
- preprotachykinin A [MeSH concept]
- protachykinin [MeSH concept]
- protachykinin [MeSH Supplementary Concept]
- tachykinin precursor 1 [HGNC gene]
OMIM relation
- Tachykinin 1 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- TAC1 Gene [NCIt concept]
gene_product_plays_role_in_biological_process
- Intercellular Communication Process [NCIt concept]
- Muscle Contraction [NCIt concept]
- Neuronal Transmission [NCIt concept]

Keyword's position in hierarchy(ies) :

You can consult :

recommendations
documents concerning education
documents for patients