Preferred Label : Darovasertib;
NCIt synonyms : Protein Kinase C Inhibitor IDE196; PKC Inhibitor IDE196; Protein Kinase C Inhibitor LXS196;
NCIt definition : An orally available protein kinase C (PKC) inhibitor with potential immunosuppressive
and antineoplastic activities. Upon oral administration, darovasertib inds to and
inhibits PKC, which prevents the activation of PKC-mediated signaling pathways. This
may lead to the induction of cell cycle arrest and apoptosis in susceptible tumor
cells. PKC, a serine/threonine protein kinase overexpressed in certain types of cancer
cells, is involved in tumor cell differentiation, proliferation, invasion and survival.;
UNII : E0YF0M8O09;
InChIKey : XXJXHXJWQSCNPX-UHFFFAOYSA-N;
CAS number : 1874276-76-2;
Molecule name : LXS196; IDE 196; IDE-196;
NCI Metathesaurus CUI : CL503026;
Origin ID : C124796;
UMLS CUI : C5446296;
Semantic type(s)
- concept_is_in_subset
- has_target
