Sumatriptan - CISMeF

Preferred Label : Sumatriptan;

NCIt definition : A sulfonamide triptan with vasoconstrictor activity. Sumatriptan selectively binds to and activates serotonin 5-HT1D receptors in the central nervous system (CNS), thereby constricting cerebral blood vessels. This may lead to a relief in pain from vascular headaches. Sumatriptan may also relieve vascular headaches by decreasing the release of vasoactive neuropeptides from perivascular trigeminal axons in the dura mater during a migraine, by reducing extravasation of plasma proteins, and by decreasing the release of other mediators of inflammation from the trigeminal nerve.;

UNII : 8R78F6L9VO;

InChIKey : KQKPFRSPSRPDEB-UHFFFAOYSA-N;

CAS number : 103628-46-2;

Chemical formula : C14H21N3O2S;

ChEBI ID : CHEBI:10650;

Details

Origin ID

C1240;

UMLS CUI

C0075632;

Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Product containing sumatriptan (medicinal product) [SNOMED CT concept]
- SUMAtriptan [LOINC component]
- Sumatriptan [ICD-11 Extension code]
- Sumatriptan (substance) [SNOMED CT concept]
- sumatriptan [ATC Code]
- sumatriptan [Substance BNPC]
- sumatriptan [MeSH Descriptor]
- sumatriptan [MeSH concept]
Validated automatic mappings to BTNT
- sumatriptan [ATC Code]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
has_salt_form
- Sumatriptan Succinate [NCIt concept]
is_free_acid_or_base_form_of
- Sumatriptan Succinate [NCIt concept]

Keyword's position in hierarchy(ies) :

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