Preferred Label : Zinc Protoporphyrin;
NCIt synonyms : Protoporphyrin IX, Zinc Chelate; (SP-4-2)-Dihydrogen (7,12-Diethenyl-3,8,13,17-Tetramethyl-21H,23H-Porphine-2,18-Dipropanoato(4-)-
N(21),N(22),N(23),N(24))Zincate(2-); Zinc Protoporphyrin IX; ZnPP; ZP; ZPP; Dihydrogen (3,8,13,17-Tetramethyl-7,12-Divinyl-21H,23H-Porphine-2,18-Dipropionato(4-)-N21,N22,N23,N24)Zincate(4-); Zincate(2-), (7,12-Diethenyl-3,8,13,17-Tetramethyl-21H,23H-Porphine-2,18-Dipropanoato(4-)-KappaN21,KappaN22,KappaN23,KappaN24)-,
Hydrogen (1:2), (SP-4-2)-; Zinc-Protoporphyrin;
NCIt definition : An ionized form of the tetrazole protoporphryin IX that contains zinc in the metal
ion binding pocket. Zinc protoporphyrin (ZPP) is formed in circulating red blood cells
(RBC) either in the presence of lead or in the absence of sufficient iron, as both
of these conditions inhibit the insertion of a ferrous ion into protoporphryin IX
to form heme. Therefore, elevated levels of ZPP is associated with heme deficiency.
Elevated RBC molar ratios of ZPP to heme are indicative of multiple pathologies including
lead poisoning, iron deficiency, protoporphyria, and various types of anemia.;
UNII : LNV3FKZ7GR;
CAS number : 15442-64-5;
Origin ID : C123793;
UMLS CUI : C0078791;
Automatic exact mappings (from CISMeF team)
- Currated CISMeF NLP mapping
- Semantic type(s)
- UMLS correspondences (same concept)
- concept_is_in_subset
