Salivary Gland Secretory Carcinoma

Preferred Label : Salivary Gland Secretory Carcinoma;

NCIt synonyms : Salivary Gland MASC; Mammary Analogue Secretory Carcinoma of Salivary Gland;

NCIt definition : A rare, low-grade carcinoma of the salivary gland that shares histopathologic features and molecular characteristics (ETV6 gene rearrangement) with secretory breast carcinoma. It usually arises from the parotid gland and less often from the minor salivary glands and has a favorable clinical outcome.;

Neoplastic status : Malignant;

NCI Metathesaurus CUI : CL512709;

Details

Origin ID

C123384;

UMLS CUI

C4330658;

Disease excludes abnormal cell
- Malignant Squamous Cell [NCIt concept]
- Malignant Stromal Cell [NCIt concept]
- Neoplastic Smooth Muscle Cell [NCIt concept]
- Neoplastic Squamous Cell [NCIt concept]
Disease may have findings
- Favorable Clinical Outcome [NCIt concept]
Excludes anatomical site(s)
- Breast [NCIt concept]
Has associated anatomic sites
- Head and Neck [NCIt concept]
- Salivary Gland [NCIt concept]
Semantic type(s)
- Neoplastic Process [UMLS semantic type]
disease_excludes_finding
- Benign Cellular Infiltrate [NCIt concept]
- Mixed Neoplastic Glandular and Squamous Cell Population [NCIt concept]
disease_has_abnormal_cell
- Adenocarcinoma Cell [NCIt concept]
- Adenocarcinoma Cell with Abundant Pale Cytoplasm [NCIt concept]
- Malignant Cell [NCIt concept]
- Malignant Epithelial Cell [NCIt concept]
- Neoplastic Cell [NCIt concept]
- Neoplastic Epithelial Cell [NCIt concept]
- Neoplastic Glandular Cell [NCIt concept]
disease_has_finding
- Carcinomatous Component Present [NCIt concept]
- Epithelial Component Present [NCIt concept]
- Low Grade Lesion [NCIt concept]
- Malignant Cellular Infiltrate [NCIt concept]
disease_has_normal_cell_origin
- Epithelial Cell [NCIt concept]
disease_has_normal_tissue_origin
- Epithelial Tissue [NCIt concept]
disease_has_primary_anatomic_site
- Head and Neck [NCIt concept]
- Salivary Gland [NCIt concept]
disease_mapped_to_gene
- ETV6/NTRK3 Fusion Gene [NCIt concept]
disease_may_have_cytogenetic_abnormality
- t(12;15)(p13;q25) [NCIt concept]
disease_may_have_molecular_abnormality
- ETV6-NTRK3 Fusion Protein Expression [NCIt concept]
pathogenesis_of_disease_involves_gene
- ETV6/NTRK3 Fusion Gene [NCIt concept]

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