NCIt synonyms : NAB2-STAT6 Fusion Protein; NGFI-A-Binding Protein 2/Signal Transducer and Activator of Transcription 6 Fusion
Protein; NAB2::STAT6 Fusion Protein;
NCIt definition : A fusion protein that is encoded by the NAB2/STAT6 fusion gene. This protein contains
the N-terminal early growth response (EGR)-binding domain of NGFI-A-binding protein
2 fused to part of signal transducer and activator of transcription 6 protein that
includes its DNA-binding transcriptional activation domain.;
NCIt note : The NAB2/STAT6 fusion protein may both induce cell proliferation and activate the
expression of EGR responsive genes. (Nature Genetics. 2013; 45:180-185.);
Semantic type(s)