Leucine-Rich Repeats and Immunoglobulin-Like Domains Protein Family

Preferred Label : Leucine-Rich Repeats and Immunoglobulin-Like Domains Protein Family;

NCIt synonyms : Leucine-Rich Repeats and Immunoglobulin-Like Domains Protein; LIG Family; LRIG Family; LRIG; LIG;

NCIt definition : A family of membrane bound proteins comprised of 15 leucine-rich repeats that are flanked both N- and C- terminally by cysteine-rich regions, three C2-type immunoglobulin-like domains, a transmembrane domain, and a cytoplasmic tail. The members of this protein family may be involved in the suppression of growth factor receptor signaling.;

PubMed : 15203213;

Details

Origin ID

C122769;

UMLS CUI

C4050247;

Automatic exact mappings (from CISMeF team)
- Lip [LOINC System]
- lip [MeSH Descriptor]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Immunoglobulin Family Gene [NCIt concept]
gene_product_has_structural_domain_or_motif
- Cysteine-Rich Domain [NCIt concept]
- Cytoplasmic Domain [NCIt concept]
- Immunoglobulin Domain [NCIt concept]
- Immunoglobulin-Like C2-Type Domain [NCIt concept]
- Leucine-Rich Repeat [NCIt concept]
- Transmembrane Domain [NCIt concept]
is_chemical_classification_of_gene_product
- Leucine-Rich Repeats and Immunoglobulin-Like Domains Protein 1 [NCIt concept]
- Leucine-Rich Repeats and Immunoglobulin-Like Domains Protein 3 [NCIt concept]

Keyword's position in hierarchy(ies) :

You can consult :

recommendations
documents concerning education
documents for patients