NCIt definition : A chimeric monoclonal antibody directed against human CD20, with potential antineoplastic
activity. Ripertamab binds to the B-cell-specific cell surface antigen CD20, which
triggers an immune response against CD20-positive B-cells, leading to apoptosis. CD20,
a non-glycosylated cell surface phosphoprotein, is exclusively expressed on B-cells
during most stages of B-cell development and is often overexpressed in B-cell malignancies.;